Lancet neurology

The most recent articles from: Lancet Neurol March 2010

Lancet neurology · Mar 2010

Review

Gluten sensitivity: from gut to brain.

Gluten sensitivity is a systemic autoimmune disease with diverse manifestations. This disorder is characterised by abnormal immunological responsiveness to ingested gluten in genetically susceptible individuals. ⋯ Furthermore, the concept of extraintestinal presentations without enteropathy has only recently become accepted. In this Personal View, we review the range of neurological manifestations of gluten sensitivity and discuss recent advances in the diagnosis and understanding of the pathophysiological mechanisms underlying neurological dysfunction related to gluten sensitivity.

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Lancet neurology · Mar 2010

Meta Analysis Comparative Study

Adjunctive dexamethasone in bacterial meningitis: a meta-analysis of individual patient data.

Dexamethasone improves outcome for some patients with bacterial meningitis, but not others. We aimed to identify which patients are most likely to benefit from dexamethasone treatment. ⋯ Wellcome Trust UK.

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