Lancet neurology
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People with epilepsy are burdened with the apparent unpredictability of seizures. In the past decade, converging evidence from studies using chronic EEG (cEEG) revealed that epileptic brain activity shows robust cycles, operating over hours (circadian) and days (multidien). We hypothesised that these cycles can be leveraged to estimate future seizure probability, and we tested the feasibility of forecasting seizures days in advance. ⋯ None. VIDEO ABSTRACT.
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Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study.
The genetic basis of variation in the progression of primary tauopathies has not been determined. We aimed to identify genetic determinants of survival in progressive supranuclear palsy (PSP). ⋯ PSP Association, CBD Solutions, Medical Research Council (UK).