Ugeskrift for laeger
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We investigated the guidelines for patient selection and drug regimens for use of antibiotic prophylaxis in relation to Caesarean section in the maternity clinics in Denmark. A questionnaire was sent to all the Danish maternity clinics that perform Caesarean section, concerning indications for use of antibiotic prophylaxis and antibiotic regimens to patients undergoing acute and elective Caesarean section. All departments (n = 48) returned the questionnaire. ⋯ The most frequent first choice drug was cefuroxim, employed by 27 departments (56%). Concerning timing, 21 departments (44%) gave antibiotics after cord clamping and 13 departments (27%) before incision. We propose a nation-wide prospective investigation on the rate of infections associated with Caesarean section to set up rational guidelines for antibiotic prophylaxis.
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Ugeskrift for laeger · Feb 1997
Review[Tuberculosis and the HIV pandemic. Risk of nosocomial tuberculosis infection].
Spread of human immunodeficiency virus (HIV) infection has had a major impact on the epidemiology of tuberculosis. In several African countries the incidence of tuberculosis has doubled, and the prevalence of HIV infection among patients with tuberculosis is 20 to 60%. A similar change has occurred in some developed countries. ⋯ The mortality among patients has been high, and there have been several cases of transmission to healthcare workers. Analyses of these recent outbreaks indicate that it is possible to intervene by well known prophylactic measures. Rapid diagnosis and treatment, and correct isolation procedures are essential to prevent outbreaks.
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Ugeskrift for laeger · Feb 1997
Clinical Trial Controlled Clinical Trial[Continuous measurements of cardiac output in the perioperative period].
Management of critically ill patients is based on knowledge of fundamental physiological variables. Automatized and continuous measurement of these variables is preferable. A new system based upon the thermodilution method has been developed to measure cardiac output automatically and continuously. ⋯ In conclusion, the CCO measurement technique is a promising clinical method. The method is straightforward, requires no calibration, is independent of vascular geometry and measures with its limitations volumetric flow. Finally automatic and continuous patient monitoring provides more information and has potential to reveal previously undetected haemodynamic events.