Ugeskrift for laeger
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Inhaled nitric oxide (iNO) has been extensively used in the treatment of severe hypoxaemic respiratory failure and/or pulmonary hypertension. Although the majority of studies have almost consistently demonstrated a beneficial effect on oxygenation and a reduction in pulmonary artery pressures, none of the randomised trials have reported a reduced mortality using iNO on patients with severe respiratory failure. In neonates with severe respiratory failure and pulmonary hypertension, however, iNO can reduce the need of extracorporal membrane oxygenation. Prior to using iNO on adult patients we suggest other measures to be taken (i.e. optimising ventilator settings, ventilation in prone position).
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Ugeskrift for laeger · Jan 2000
Clinical Trial Controlled Clinical Trial[Predictive factors of the effect of multidisciplinary, intensive rehabilitation of back pain. Demographic, socioeconomic and physical factors].
In order to identify possible predictive factors for success from rehabilitation in a functional restoration (FR) program for patients with chronic low back pain, pre-treatment baseline variables were correlated to different outcome parameters following treatment in either a FR program or control programs. A prospective clinical trial involving 816 patients was carried out. Of the total cohort 621 patients participated in a FR program and 195 in control groups. The results showed that different factors could be identified as useful in predicting outcome from a FR program, but most of these factors were also shown to predict success for controls of shorter outpatient programs or of no treatment.
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Ugeskrift for laeger · Jan 2000
[Prolonged neck pain following automobile accidents. Gender and age related risk calculated on basis of data from an emergency department].
Whiplash injuries following road traffic accidents seem to be an increasing problem in many countries. Many studies are based on biased material from specialized departments or data from insurance companies. The aim of this study was to calculate the risk of longer lasting neck pain for persons involved in road traffic accidents and treated in the emergency room. ⋯ Accidents with front to back collisions presented the highest risk. The conclusion was that whiplash associated disorders following road traffic accidents in motor vehicles apparently is a large problem. The treatment and rehabilitation must be centralized at the level of the general practitioners.