Ugeskrift for laeger
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Ugeskrift for laeger · Aug 2012
[A procalcitonin-guided algorithm for pneumonia may reduce antibiotic use and treatment duration].
Reduction of antimicrobial resistance in microorganisms is imperative. Pneumonia is important in this matter because of its high incidence, subjective diagnostic criteria, and variations in aetiology. Research has focused on the use of a procalcitonin-guided algorithm for antimicrobial stewardship with promising reductions in antibiotic use and treatment duration, but more research is needed in order to draw a final conclusion. Lack of objective diagnostic criteria, methodological challenges in research, a future focus on primary care, and the need for a cost-benefit analysis should be considered.
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Ugeskrift for laeger · Aug 2012
[Sublingual immunotherapy in children with grass pollen induced allergic rhinoconjunctivitis].
Specific immunotherapy is the only current treatment that may modify the disease process in allergic rhinoconjunctivitis. Recent studies have evidenced that sublingual administration of grass extract tablets is an efficacious, safe and convenient form of specific immunotherapy in children with grass pollen induced allergic rhinoconjunctivitis. It is recommended that daily treatment is initiated four months before the pollen season begins and continued through three years, though paediatric studies of long-term and potential asthma and allergy prevention effects are still awaited.
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Ugeskrift for laeger · Aug 2012
Case Reports[Dyskinesia after treatment with droperidol for preventing postoperative nausea and vomiting].
This case presents a young woman with extrapyramidal reactions after the use of a small dose (0.625 mg) of droperidol. In combination with dexamethason (8 mg) droperidol was given as the patient underwent laparoscopic cholecystectomy in order to prevent postoperative nausea and vomiting. ⋯ We believe that droperidol was the cause. She had previously experienced similar signs after taking metoclopramide.
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Hereditary angio-oedema (HAE) is a rare genetic disease caused by deficiency of complement C1 inhibitor. It is characterised by recurrent episodes of subcutaneous or submucosal oedema typically involving the extremities, bowel, face or larynx. Within the latest years it has become evident that the active mediator of HAE attacks is an increased level of bradykinin and various new treatment modalities have been developed. The aim of this paper is to give an update from the Danish HAE Comprehensive Care Centre on current treatment possibilities and address some of the challenges when diagnosing HAE.
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As general anaesthesia (GA) for caesarean section (CS) compared to regional anaesthesia (RA) can increase maternal risks, it has been suggested that 85% of all acute CS should be performed in RA. We observed whether anaesthesiologists at a Danish university hospital over a 4,5 year-period fulfilled this objective. ⋯ Our results indicate that anaesthetising for CS routinely helps to keep the frequency of RA for CS above 85%. Further studies are necessary to investigate whether GA for CS is used according to recommendations.