African health sciences
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African health sciences · Jun 2011
Evaluation of the LTK63 adjuvant effect on cellular immune responses to measles virus nucleoprotein.
A lot of pathogens enter the body via the nasal route. The construction of non-toxic mutants of heat labile Escherichia coli enterotoxin (LT), which is a potent mucosal adjuvant, represents a major breakthrough for the development of mucosal vaccines. ⋯ These data further demonstrate the great potential of LTK63 as a safe mucosal vaccine adjuvant.
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Late presentation of breast carcinoma is common in resource-limited countries with attendant poor outcome. ⋯ Metastatic disease is common in Nigeria and treatment is limited due to resource limitations. Improved awareness of the disease is advocated to reduce late presentation.
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African health sciences · Jun 2011
Factors affecting quality of life in cancer patients undergoing chemotherapy.
Cancer can produce many different symptoms, some subtle and some not at all subtle. An increasingly important issue in oncology is to evaluate quality of life (QoL) in cancer patients. The cancer-specific QoL is related to all stages of this disease. ⋯ Cancer is an important health issue influencing QoL. An appropriate treatment which may provide care to the cancer patients is CT. A CT cycle may improve QoL in patients with solid tumors.
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Suicide was investigated in the urban setting of Kampala, Uganda. ⋯ The retrospective review of records at Mulago hospital was beset by incomplete records whereas a pilot psychological autopsy study was well accepted and might contribute valuable data in African settings.
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African health sciences · Jun 2011
Uterine Leiomyomata in South Western Nigeria: a clinical study of presentations and management outcome.
Uterine leiomyoma is remarkably common, however only a subset of women have their fibroids clinically detected, symptomatic, or warrant surgical treatment. Its removal is commonly associated with complications. To prevent or control the occurrence of this complication requires the understanding of the factors associated with the complications. ⋯ Uterine fibroid is common in our environment and its removal is commonly associated with post-operative pyrexia, blood loss, and anaemia and wound infection. Midline incision, closure of rectus sheet with chromic catgut and myomectomy were associated with postoperative complications in this review.