African health sciences
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African health sciences · Dec 2013
Antihypercholesterolemic activity of ethanolic extract of Buchholzia coriacea in rats.
Hypercholesterolemia is a condition characterised with high level of cholesterol in the blood. ⋯ The results suggest that Buchholzia coriacea seeds contain potent antihypercholesterolemic agent which may find clinical application in ameliorating hypercholesterolemia and its attendant complications.
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African health sciences · Dec 2013
ReviewA review of the management of perforated duodenal ulcers at a tertiary hospital in south western Nigeria.
Gastro-duodenal perforations are common and may complicate peptic ulcer disease. Management is often by surgical closure. ⋯ Late presentation of duodenal ulcer perforation is common with high mortality. Pragmatic surgical intervention with Graham's omentopexy with broad spectrum antibiotics is still commonly practiced.
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African health sciences · Dec 2013
Decompensated cirrhosis-related admissions in a large urban hospital in Uganda: prevalence, clinical and laboratory features and implications for planning patient management.
Cirrhosis-related complications are a major cause of morbidity and mortality in areas where its risk factors are endemic. ⋯ Cirrhosis is common in Mulago hospital presenting mainly with ascites and variceal bleeding. Aside from controlling causes of liver diseases, especially alcohol and hepatitis B virus infection, in the interim it is necessary to manage complications in patients who already have cirrhosis.
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African health sciences · Dec 2013
Causes and outcome of hospitalization among HIV-infected adults receiving antiretroviral therapy in Mulago hospital, Uganda.
Cohorts describing cause specific mortality in HIV-infected patients initiating antiretroviral therapy (ART) operate on an outpatient basis. Hospitalized patients represent the spectrum and burden of severe morbidity and mortality in patients on ART. ⋯ Opportunistic infections, malignancy and AZT-associated anemia contributed to most hospitalizations and mortality. It is important to intensify prevention, screening, and treatment for these opportunistic diseases and early ART initiation in HIV-infected patients. Tenofovir-based regimens, unless contraindicated should be scaled up to replace AZT-based regimens as first line ART drugs.