African health sciences
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African health sciences · Dec 2020
Association between osteoporosis and hepatitis B cirrhosis: a case-control study.
Hepatitis B virus (HBV)-related cirrhosis is associated with decreased bone mineral density (BMD); however, the mechanism is yet unknown. To assess the incidence of osteoporosis in patients with HBV-associated cirrhosis and relevant mechanisms. ⋯ Enhanced bone resorption accounted for increased risk of osteoporosis in severe cirrhosis. Thus, HBV-associated cirrhosis was a risk factor for osteoporosis.
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African health sciences · Dec 2020
The relationship between sleep quality and dyspnoea severity in patients with COPD.
This study aimed to determine sleep quality, frequency and severity of dyspnoea in COPD patients and to evaluate the relationship between dyspnoea severity and sleep quality. ⋯ It was concluded that the majority of COPD patients had moderate or poor sleep quality and dyspnoea. As dyspnoea severity increases, sleep quality decreases.
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African health sciences · Dec 2020
Aerobic exercise affects sleep, psychological wellbeing and immune system parameters among subjects with chronic primary insomnia.
Chronic primary insomnia is characterized by long-term difficulties in maintaining and initiating sleep, too early waking up, poor mood, fatigue, impaired concentration and poor quality of life. Exercise training is recommended to prevent and alleviate sleep disorders. ⋯ Exercise training can be considered as a non-pharmacological modalty for modifying sleep quality, psychological wellbeing and immune system among subjects with chronic primary insomnia.
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African health sciences · Dec 2020
Meta AnalysisAssociation between APOC3 polymorphisms and non-alcoholic fatty liver disease risk: a meta-analysis.
The apolipoprotein C3 (APOC3) polymorphism has been reported to predispose to non-alcoholic fatty liver disease (NAFLD). However, the results remain inconclusive. This meta-analysis aimed to provide insights into the association between APOC3 polymorphisms and NAFLD risk. ⋯ The meta-analyses suggests that the rs2854116 polymorphism but not rs2854117 polymorphism in APOC3 gene might be a risk factor for NAFLD among Asians. That is, individuals with CT+CC genotype have higher risk of developing NAFLD. However, studies with sufficient sample size are needed for the further validation.
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African health sciences · Dec 2020
Multicenter Study Observational StudyAntibiotic prescribing practices in three neonatology units in Kigali, Rwanda. - an observational study.
There is limited published data on antibiotic use in neonatal units in resource-poor settings. ⋯ The median antibiotic duration for neonates with normal lab results exceeded the recommended duration mandated by the national neonatal protocol. We recommend the development of antibiotic stewardship programs in neonatal units in Rwanda to prevent the adverse effects which may be caused by inappropriate or excessive use of antibiotics.