African health sciences
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African health sciences · Dec 2020
Modelling CD4 counts before and after HAART for HIV infected patients in KwaZulu-Natal South Africa.
This study aims to make use of a longitudinal data modelling approach to analyze data on the number of CD4+cell counts measured repeatedly in HIV-1 Subtype C infected women enrolled in the Acute Infection Study of the Centre for the AIDS Programme of Research in South Africa. ⋯ Effective HAART initiation immediately after HIV exposure is necessary to suppress the increase of viral loads to induce potential ART benefits that accrue over time. The data showed evidence of strong individual-specific effects on the evolution of CD4+ counts. Effective monitoring and modelling of disease biomarkers are essential to help inform methods that can be put in place to suppress viral loads for maximum ART benefits that can be accrued over time at an individual level.
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African health sciences · Dec 2020
Acute effects of electronic cigarette smoking on ventricular repolarization in adults.
Electronic cigarette (e-cigarette) use is constantly increasing. However, the association between e-cigarette use and ventricular arrhythmia is unknown. Thus, in this study, we aimed to evaluate the markers of ventricular repolarization such as QT interval, corrected QT (QTc), QT dispersion (QTd), peak-to-end interval of the T wave (Tp-e), corrected Tp-e and Tp-e/QT ratios in e-cigarette users. ⋯ This is the first study to show the disruption of ventricular repolarization properties in e-cigarette users. E-cigarette use in terms of public health leads to augmentation of transmural dispersion of repolarization, which may be potential indicator of ventricular arrhythmogenesis.
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African health sciences · Dec 2020
Infertility and associated factors in three hospitals in Douala, Cameroon: a cross-sectional study.
We determined the prevalence and factors associated with couple infertility in three hospitals in Douala, Cameroon. ⋯ One in every five couples in this study was infertile. Several factors affect the risks associated with couple infertility. The identification of these factors could help detect subgroups of couples at high risk of infertility. Reproductive health education, screening programmes for STI's that may lead to infertility should be offered to couples.
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African health sciences · Dec 2020
Prevalence of Helicobacter pylori infection among children with primary nephrotic syndrome: a cross-sectional study.
Limited data are available about the prevalence of helicobacter pylori (H.pylori) infection among primary NS children. ⋯ The current study negates the increased risk of H.pylori infection in children with primary NS.
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African health sciences · Dec 2020
The impact of menopause on sexual function in women and their spouses.
The purpose of this study is to evaluate the impact of menopause on sexual function in women and their spouses. ⋯ Although, significant correlations between male erectile function and menopausal female sexual function have not identified; but, low scores of the subscales of FSFI in female participants mostly impaired sexual satisfaction and overall satisfaction in their spouses.