African health sciences
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African health sciences · Jun 2021
Potential anticancer activity of Acetone extracts of Toona cilliata, Seriphium plumosum and Schkuhria pinnata on HeLa cervical cancer cells.
Cervical cancer is common in women in less developed regions of the world. The plant biomolecules can be employed for synergistic activity with chemo- and radiotherapy. This combinations might result in reduced toxicity and increased efficacy of the treatment regimen. ⋯ Observable concentration dependent cell proliferation inhibition by test materials was exhibited. The leaf extracts from T. cilliata, S. plumosum and S. pinnata contain compounds of various polarities with free-radical, antioxidant and anti-cancerous activities that may play a beneficial role in treatment.
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African health sciences · Jun 2021
Co-existence of NDM-1 and OXA-48 genes in Carbapenem Resistant Klebsiella pneumoniae clinical isolates in Kafrelsheikh, Egypt.
The noteworthy spread of carbapenem-resistant K. pneumoniae (CR-KP) isolates represents a significant safety threat. ⋯ This study reported a high incidence of MDR profile with the emergence of blaNDM-1 and blaOXA-48 genes co-existence in CR-KP isolates in Kafrelsheikh, Egypt. Hence, more restrictions should be applied against the spread of such serious pathogens.
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African health sciences · Jun 2021
Psycho-social problems of adolescents with sickle-cell anaemia in Ekiti State, Nigeria.
Sickle-cell disease comprises a group of genetic disorders characterized by the inheritance of sickle haemoglobin from both parents. Sickle-cell disease carries a huge psycho-social burden which has impacts on the physical, psychological, social and occupational well-being as well as levels of independence on adolescents. ⋯ Majority of the respondents attested to the psycho-social problems facing adolescents with sickle-cell anaemia. Based on the findings of the study, it was recommended that social workers should be employed in health sectors; government should offered standard health care for all adolescents with sickle cell disease.