African health sciences
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African health sciences · Dec 2020
Evaluation of MRI Artifact in some selected centers in Kano Metropolis, Nigeria.
Magnetic Resonance Imaging (MRI) artifacts can occur due to hardware or software related problems, human physiologic phenomenon or physical restrictions. Careful study design and scanning protocols can prevent certain artifacts from occurring, but some are unavoidable. ⋯ In Kano metropolis the most encountered MRI artifact was the motion-induced artifact and thoracic spine MRI had the highest number of artifacts. The artifacts had a negative effect on image quality.
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African health sciences · Dec 2020
Trace metal toxicity in some food items in three major markets in Ado-Odo/Ota LGA, Ogun State, Nigeria and associated health implications.
Many of the markets in Nigeria are open, where foodstuffs are laid bare on flat trays and open baskets, directly exposing them to environmental contaminants. This study aimed at determining whether some food items on sale around an industrialized area of Ogun State are contaminated with trace metals. ⋯ Some of the food items consumed in this area are not entirely safe from metal toxicity and this may have serious health consequences.
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African health sciences · Dec 2020
Aerobic exercise affects sleep, psychological wellbeing and immune system parameters among subjects with chronic primary insomnia.
Chronic primary insomnia is characterized by long-term difficulties in maintaining and initiating sleep, too early waking up, poor mood, fatigue, impaired concentration and poor quality of life. Exercise training is recommended to prevent and alleviate sleep disorders. ⋯ Exercise training can be considered as a non-pharmacological modalty for modifying sleep quality, psychological wellbeing and immune system among subjects with chronic primary insomnia.
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African health sciences · Dec 2020
Improved antimalarial activity of caprol-based nanostructured lipid carriers encapsulating artemether-lumefantrine for oral administration.
Artemether and lumefantrine display low aqueous solubility leading to poor release profile; hence the need for the use of lipid-based systems to improve their oral bioavailability so as to improve their therapeutic efficacy. ⋯ This study has shown the potential of caprol-based NLCs for significant improvement in oral bioavailability and hence antimalarial activity of poorly soluble artemether and lumefantrine. Importantly, this would improve patient compliance due to decrease in dosing frequency as a sustained release formulation.
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African health sciences · Dec 2020
In vivo studies on the biochemical indices of Plasmodium berghei infected mice treated with Alstonia boonei leaf and root extracts.
A study on the biochemical indices of albino mice infected with Plasmodium berghei and treated with Alstonia boonei aqueous and ethanolic extracts was undertaken. ⋯ The antiplasmodial potentials of A. boonei leaf and root extracts were dosage and duration-dependent, and have demonstrated satisfactory normalization of altered biochemical indices due to malaria.