African health sciences
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African health sciences · Jun 2018
Interleukin-6 gene -572G/C polymorphism and prostate cancer risk.
The aim of the present study was to determine whether the interleukin-6 (IL-6) -572G/C polymorphism correlates with prostate cancer. ⋯ Our findings demonstrated that the -572G/C polymorphism of the IL-6 gene may be a risk factor for the development of prostate cancer in Asians.
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African health sciences · Jun 2018
Impact of weight reduction on selected immune system response among Hepatitis C virus Saudi patients.
Recently, about 2.35% of the world populations are estimated to be chronically infected with hepatitis C virus (HCV). Previous cohort studies indicated that obesity increases risk of hepatic steatosis and fibrosis in non-diabetic patients with chronic hepatitis C infection due to diminished response to anti-viral therapy and as a result obesity is considered as an important factor in the progression of chronic HCV. However, there is a strong association between BMI and the human immune system among HCV patients. ⋯ Weight loss modulates immune system parameters of patients with HCV.
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African health sciences · Jun 2018
Quinine inhibits ovulation and produces oxidative stress in the ovary of cyclic Sprague-Dawley rats.
Quinine has been reported to possess anti-spermatogenic activities. ⋯ Quinine completely blocks ovulation, suppresses LH surge, and produces oxidative stress in the ovary.