African health sciences
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African health sciences · Dec 2016
Glyceryl trinitrate is a novel inhibitor of quorum sensing in Pseudomonas aeruginosa.
Targeting quorum sensing is an alternative approach to antibiotics.Targeting quorum sensing-regulated virulence will disarm the pathogen without exerting pressure on its growth. As a result, emergence of resistance is avoided and the immune system can easily eradicate bacteria. ⋯ Glyceryl trinitrate can be an antivirulence agent in the treatment of Pseudomonas aeruginosa topical infections such as burn infections.
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African health sciences · Dec 2016
Chemical constituents of Cyperus rotundus L. and their inhibitory effects on uterine fibroids.
Xiang Fu (Cyperus rotundus L) enters the liver, spleen and triple warmer meridians, and has qi stagnation-removing, qi circulation-promoting, menstruation-regulating and pain-relieving effects. Besides, it can improve ovarian function, and has hypolipidemic, hypoglycemic and neuroprotective actions. ⋯ It concludes that amentoflavone has a significant inhibitory effect on uterine tumors in rats. Its mechanism may be by elevating Bax protein expression, down-regulating Bcl-2 expression, forming homodimers Bax/Bax, and reducing plasma estradiol and progesterone to promote apoptosis of uterine fibroid cells.
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African health sciences · Dec 2016
ReviewA systematic review of factors affecting energy intake of adolescent girls.
Adolescence is considered a critical period marked by an increase in energy intake to meet the body's physiological needs especially during puberty. This study reviews existing literature and critically analyses factors associated with eating habits and energy intake of adolescent girls. ⋯ There is a dire need to consider factors associated with EI when designing nutritional intervention programs to prevent health problems in adulthood. The goal is not to change behavior of all but to increase the percentage of people adopting healthier lifestyle.
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African health sciences · Dec 2016
An anatomical and osteometric study of the femoral sulcus angle in adult Malawians.
Femoral sulcus angle is particularly important in clinical evaluation of patellofemoral joint. Individuals show considerable differences in asymmetrical dimensions of the femur. ⋯ This study has provided the mean size of the femoral sulcus angle of adult Malawians. These findings suggest that the size of the sulcus angle cannot determine gender among adult black Malawians suggesting the interpretation that femora asymmetric dimensions are population specific, which should be considered in the patellofemoral joint evaluation.
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African health sciences · Sep 2016
Randomized Controlled TrialEfficacy of early skin-to-skin contact on the rate of exclusive breastfeeding in term neonates: a randomized controlled trial.
Despite multiple benefits of breast milk, the rates of exclusive breastfeeding in developing countries are low. ⋯ Early SSC significantly improved the rate of exclusively breastfeeding at 6 weeks of age among healthy term neonates. An important additional effect was a decrease in the amount of pain that mothers in the SSC group experienced during episiotomy repair.