Arthritis research & therapy
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Arthritis Res. Ther. · Jul 2014
Multicenter Study Clinical TrialVenous thromboembolism after total joint arthroplasty: results from a Japanese multicenter cohort study.
Real-world evidence of the effectiveness of pharmacological thromboprophylaxis for venous thromboembolism (VTE) is limited. Our objective was to assess the effectiveness and safety of thromboprophylactic regimens in Japanese patients undergoing joint replacement in a real-world setting. ⋯ These findings indicate that prophylaxis with fondaparinux, not enoxaparin, reduces the risk of DVT but increases bleeding tendency in patients undergoing TKA and THA.