Neurocritical care
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Randomized Controlled Trial Comparative Study
A prospective evaluation of labetalol versus nicardipine for blood pressure management in patients with acute stroke.
Acute hypertension is common following stroke and contributes to poor outcomes. Labetalol and nicardipine are often used for acute hypertension but there are little data comparing the two. This study is to evaluate the therapeutic response and tolerability of these two agents following acute stroke. ⋯ In acutely hypertensive stroke patients, superior therapeutic response was achieved with nicardipine versus labetalol. Despite this, there was no demonstrable difference in clinical outcomes.