IEEE transactions on bio-medical engineering
-
This paper shows the development of a system to control inhalation anesthetic concentration delivered to a patient based upon that patient's midlatency auditory evoked potentials (MLAEP's). It was developed and tested in dogs by determining response to the supramaximal stimulus of tail clamping. Prior to tail clamp, the MLAEP was recorded along with inhalational anesthetic concentration and classified as responders or nonresponders as determined by tail clamping. ⋯ The anesthetic controller used this ANN combined with fuzzy logic and rule-based control. A set of ten animal experiments were performed to test the robustness of this controller. Acceptable clinical performance was obtained, showing the feasibility of this approach.