IEEE transactions on bio-medical engineering
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IEEE Trans Biomed Eng · Aug 2006
Comment LetterOn the optimal defibrillation waveform--how to reconcile theory and experiment?
Medical intervention by electrical current as applied to humans or animals may have tremendous therapeutic impact if delivered while being carefully controlled. Otherwise, the situation can be harmful in terms of injury or even become lethal. ⋯ The anticipated answer is not simply a range somewhere between a maximum and a minimum, but most likely an "intelligently" selected case-specific optimum, delicately positioned between effective and unsafe. Combining insight from theory with pertinent experimental findings may offer a clearer view on an unresolved issue that often points to a cross-road of life and death.