IEEE transactions on bio-medical engineering
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IEEE Trans Biomed Eng · Nov 2005
Clinical TrialTime-varying analysis methods and models for the respiratory and cardiac system coupling in graded exercise.
The analysis of heart period series is a difficult task especially under graded exercise conditions. From all the information present in these series, we are the most interested in the coupling between respiratory and cardiac systems, known as respiratory sinus arrythmia. In this paper, we show that precise patterns concerning the respiratory frequency can be extracted from the heart period series. ⋯ Since respiration acts to modulate the sinus rhythm, we relate the frequencies and amplitudes to this modulation by analyzing in detail its nonlinear transformation giving the heart period signal. This analysis is performed assuming stationary conditions but also in the realistic case where the mean heart period, the amplitude, and the frequency of the respiration are time-varying. Since this paper is devoted to the theoretical and complete presentation of the method used in a physiological study published elsewhere, the capabilities of our method will be illustrated in a realistic simulated case.
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An electrocardiogram (ECG) data compression scheme is presented using the gain-shape vector quantization. The proposed approach utilizes the fact that ECG signals generally show redundancy among adjacent heartbeats and adjacent samples. An ECG signal is QRS detected and segmented according to the detected fiducial points. ⋯ The experimental results show that with the proposed method both visual quality and the objective quality are excellent even in low bit rates. An average PRD of 5.97% at 127 b/s is obtained for the entire 48 records in the MIT-BIH database. The proposed method also outperforms others for the same test dataset.
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IEEE Trans Biomed Eng · Oct 2005
Clinical TrialInterpretation of approximate entropy: analysis of intracranial pressure approximate entropy during acute intracranial hypertension.
We studied changes in intracranial pressure (ICP) complexity, estimated by the approximate entropy (ApEn) of the ICP signal, as subjects progressed from a state of normal ICP (< 20-25 mmHg) to acutely elevated ICP (an ICP "spike" defined as ICP > 25 mmHg for < or = 5 min). We hypothesized that the measures of intracranial pressure (ICP) complexity and irregularity would decrease during acute elevations in ICP. ⋯ This suggests that the complex regulatory mechanisms that govern intracranial pressure are disrupted during acute rises in ICP. Furthermore, we carried out a series of experiments where ApEn was used to analyze synthetic signals of different characteristics with the objective of gaining a better understanding of ApEn itself, especially its interpretation in biomedical signal analysis.
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IEEE Trans Biomed Eng · Oct 2005
Clinical TrialQualitative and quantitative evaluation of heart sound reduction from lung sound recordings.
Recursive least squares (RLS) adaptive noise cancellation (ANC) and wavelet transform (WT) ANC have been applied and compared for heart sound (HS) reduction from lung sounds (LS) recordings. Novel processes for quantitative and qualitative evaluation of any method for HS reduction from LS have also been proposed.
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Beat detection algorithms have many clinical applications including pulse oximetry, cardiac arrhythmia detection, and cardiac output monitoring. Most of these algorithms have been developed by medical device companies and are proprietary. Thus, researchers who wish to investigate pulse contour analysis must rely on manual annotations or develop their own algorithms. ⋯ The algorithm incorporates a filter bank with variable cutoff frequencies, spectral estimates of the heart rate, rank-order nonlinear filters, and decision logic. We prospectively measured the performance of the algorithm compared to expert annotations of ICP, ABP, and SpO2 signals acquired from pediatric intensive care unit patients. The algorithm achieved a sensitivity of 99.36% and positive predictivity of 98.43% on a dataset consisting of 42,539 beats.