International braz j urol : official journal of the Brazilian Society of Urology
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Randomized Controlled Trial Multicenter Study
Efficacy and safety of parecoxib in the treatment of acute renal colic: a randomized clinical trial.
Although non-selective non-steroidal anti-inflammatory drugs (nsNSAIDs) and opioids are effective treatments for acute renal colic, they are associated with adverse events (AEs). As cyclooxygenase-2 selective NSAIDs may provide a safer alternative, we compared the efficacy and safety of parecoxib versus an nsNSAID in subjects with acute renal colic. ⋯ Parecoxib is as effective as ketoprofen in the treatment of pain due to acute renal colic, is well tolerated, and has a comparable safety profile.