Medicina clinica
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The ocular ultrasound spot sign negatively predicts the success of thrombolytic treatment in retinal arterial occlusions. We evaluated the presence of the spot sign in these patients. ⋯ Ocular ultrasound is very useful in the evaluation of patients with acute retinal ischemia. More than 50% of CRAOs and one in 4 with BRAOs have the spot sign and would not benefit from systemic thrombolysis.
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The role of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) in the treatment of venous thromboembolism (VTE) in patients with antiphospholipid syndrome remains uncertain. ⋯ In APS patients with VTE, DOACs showed similar rates of recurrent thrombosis and major bleeding compared to VKAs. Future studies should therefore focus on the role of DOACs in APS patients with varying clinical and serological profiles.