Acta gastro-enterologica Belgica

The most recent articles from: April 2021

  • Acta Gastroenterol. Belg. · Apr 2021

    Seronegative autoimmune hepatitis in children: a single-center experience.

    Seronegative autoimmune hepatitis (AIH) is a diagnostic challenge with unclear prognosis. This study describes the features and outcomes of seronegative AIH in children. ⋯ Patients with seronegative AIH present frequently with acute hepatitis or ALF. AIH diagnosis can be confirmed by observing the effects of corticosteroid therapy in seronegative patients with characteristic AIH liver histopathological features. However, the presence of lymphocytopenia in seronegative patients is a sign of bone marrow failure.

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