Liver international : official journal of the International Association for the Study of the Liver
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A prospective study was carried out in 22 cirrhotic patients referred for orthotopic liver transplantation, in order to analyze serum osteoprotegerin (OPG) and RANKL levels and their relationship with metabolic bone disease. ⋯ OPG values are elevated in cirrhotic patients before liver transplantation, particularly in those with low bone mass at the proximal femur.