Liver international : official journal of the International Association for the Study of the Liver
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Randomized Controlled Trial Comparative Study
Effects of terlipressin and somatostatin on liver and thorax blood volumes in patients with cirrhosis.
Variceal bleeding in cirrhosis can cause liver ischaemia and deteriorate the hyperdynamic state; thus, the effects of vasoconstrictor therapy on liver blood volume (LBV) and thorax blood volume (ThBV) are important. ⋯ Terlipressin, but not somatostatin, maintains LBV, increases ThBV and improves the hyperdynamic state in cirrhosis. These effects can be beneficial in variceal bleeding, particularly in patients with advanced liver disease.