The lancet. Gastroenterology & hepatology
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Lancet Gastroenterol Hepatol · Nov 2016
Development and validation of a dynamic outcome prediction model for paracetamol-induced acute liver failure: a cohort study.
Early, accurate prediction of survival is central to management of patients with paracetamol-induced acute liver failure to identify those needing emergency liver transplantation. Current prognostic tools are confounded by recent improvements in outcome independent of emergency liver transplantation, and constrained by static binary outcome prediction. We aimed to develop a simple prognostic tool to reflect current outcomes and generate a dynamic updated estimation of risk of death. ⋯ Foundation for Liver Research.