Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · Feb 2022
Diagnostic and prognostic significance of long noncoding RNA LINC00173 in patients with melanoma.
A growing volume of literature has suggested long noncoding RNAs (lncRNAs) as important players in tumor progression. In this study, we aimed to investigate the expression and prognostic value of lncRNA LINC00173 (LINC00173) in melanoma. ⋯ Our data indicated that LINC00173 expression could serve as an unfavorable prognostic biomarker for melanoma patients.
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Rev Assoc Med Bras (1992) · Feb 2022
Constipation in the period of limited isolation during COVID-19 pandemic.
COVID-19 outbreak has become widespread globally and caused a new global chaos. This outbreak that completely affected the lifestyle of individuals resulted in periods of isolation. Here, we evaluated the effects of lifestyle changes with isolation on constipation. ⋯ The data of this present study demonstrated that isolation period was effective on the newly developed constipation. Decreased physical activity and water consumption are also effective on constipation.
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Rev Assoc Med Bras (1992) · Feb 2022
The epicardial fat thickness is associated with fragmented QRS in patients with newly diagnosed metabolic syndrome.
The metabolic syndrome involves both metabolic and cardiovascular risk factors and is associated with cardiovascular mortality. Epicardial fat tissue plays a crucial role in deleterious effects of metabolic syndrome on the heart, including myocardial fibrosis. The fragmented QRS reflects heterogeneous depolarization of the myocardium and occurs as a result of fibrosis. Thus, we aimed to investigate whether there is an association between fragmented QRS and epicardial fat tissue in patients with metabolic syndrome. ⋯ Epicardial fat tissue and QRS duration were independently associated with the presence of fragmented QRS. Basic echocardiographic and electrocardiographic parameters might be used for the risk stratification in metabolic syndrome patients.