Chinese medical journal
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Chinese medical journal · Sep 2019
Newly detected atrial fibrillation is associated with cortex-involved ischemic stroke.
Both cortical and cortical-subcortical (cortex-involved) lesions are typically associated with embolic stroke, of which atrial fibrillation (AF) is the common cause. The aim of this study was to find out the associations between cortex-involved stroke, vascular risk factors, and the subtypes (discovery time and duration) of AF. ⋯ NCT02156765, https://clinicaltrials.gov/ct2/show/record/NCT02156765.
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Chinese medical journal · Sep 2019
Role and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models.
Acitretin and matrine have been used in the treatment of psoriasis in China. This study was designed to investigate the role and related mechanisms of matrine alone and in combination with acitretin in the treatment of psoriasis in vitro and in vivo. ⋯ Matrine has therapeutic potentials for psoriasis. Matrine and acitretin show synergistic effect via cell cycle arrest and autophagy induction by PI3K/Akt/mTOR pathway.
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Chinese medical journal · Sep 2019
Epidemiology of Sepsis-3 in a sub-district of Beijing: secondary analysis of a population-based database.
With the publication of Sepsis-3 definition, epidemiological data based on Sepsis-3 definition from middle-income countries including China are scarce, which prohibits understanding of the disease burden of this newly defined syndrome in these settings. The purpose of this study was to describe incidence and outcome of Sepsis-3 in Yuetan sub-district of Beijing and to estimate the incidence rate of Sepsis-3 in China. ⋯ NCT02285257, https://clinicaltrials.gov/ct2/show/record/NCT02285257.