Chinese medical journal
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Chinese medical journal · Jan 2012
Meta AnalysisEfficacy and safety of micafungin for invasive candida infections: a meta-analysis of randomized controlled trials.
Invasive fungal infections such as candidiasis and mold infections cause significant morbidity and mortality in seriously ill patients. Micafungin is an echinocandin antifungal agent with potent activity against most species of Candida and Aspergillus. We did this meta-analysis to clarify whether micafungin offers superior efficacy and safety compared with other antifungal agent for treating infections associated with invasive candidiasis. ⋯ Micafungin has a good safety and tolerability profile, with an efficacy at least comparable to the other antifungal agents. Micafungin offers advantages over other agents for antifungal prophylaxis. Micafungin offers an appropriate alternative for antifungal prophylaxis rather than the treatment of invasive candida infections.
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Chinese medical journal · Jan 2012
Randomized Controlled TrialExtracorporeal shock wave treatment for non-inflammatory chronic pelvic pain syndrome: a prospective, randomized and sham-controlled study.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a clinical syndrome characterized by pain in the perineum, pelvis, suprapubic area, or external genitalia and variable degrees of voiding and ejaculatory disturbance. The analgesic effect of extracorporeal shock wave treatment (ESWT) was an interesting phenomenon with an unclear mechanism discovered by chance in the applications for urolithiasis, on which ESWT has become an increasingly popular therapeutic approach as an alternative option for the treatment of a number of soft tissue complaints. In this study, we aimed to evaluate the feasibility and efficacy of ESWT in non-inflammatory (IIIB) CP/CPPS. ⋯ ESWT exhibits a potentially therapeutic role in the treatment of CP/CPPS.
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Chinese medical journal · Jan 2012
¹¹C-methionine and ¹⁸F-fluorodeoxyglucose positron emission tomography/CT in the evaluation of patients with suspected primary and residual/recurrent gliomas.
(18)F-fluorodeoxyglucose (FDG) is the most widely used radiotracer in tumor imaging, but its use for brain gliomas and recurrence is limited by the high (18)F-FDG uptake in normal brain tissue. (11)C-methionine (MET) has low uptake in the normal brain tissue, providing potential advantages over (18)F-FDG. The aim of the study was to investigate the diagnostic value of (11)C-MET compared to (18)F-FDG positron emission tomography and computed tomography (PET/CT) in patients with suspected primary and residual/recurrent gliomas. ⋯ (11)C-MET PET/CT is superior to (18)F-FDG PET/CT in detecting and delineating gliomas and residual/recurrent tumors, especially low-grade gliomas and residual/recurrent lesions present in gray matter, but its role in non-invasive grading of the tumors is limited.
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Chinese medical journal · Jan 2012
Clinical effect of distal radius fracture treated with open reduction and internal plate fixation.
For some specific comminuted unstable intra-articular fracture, the plaster cast can not maintain the alignment of the articular surface effectively. The aim of this study was to evaluate the clinical effects of distal radius fracture treated with open reduction and internal plate fixation retrospectively. ⋯ The clinical effect of distal radius fracture treated with open reduction and internal plate fixation was relatively satisfactory. Meticulous operation procedure and individual rehabilitation strategy contribute to the wrist joint functional recovery.
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Chinese medical journal · Jan 2012
Impact of gender and body mass index on surgical outcomes following gastrectomy: an Asia-Pacific perspective.
Although surgeons may expect difficulties in performing gastrectomy on patients with high body mass index (BMI), it is not always the case, especially regarding patient gender. The aim of this study was to evaluate gender as a predictive factor of surgical outcomes related to obesity, as defined by the World Health Organization for the Asia-Pacific region. ⋯ Disparity in surgical outcomes between male and female patients does exist, particularly in patients with high BMI. Gender adjustment of BMI must be performed when predicting surgical outcomes.