Expert review of anti-infective therapy
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Expert Rev Anti Infect Ther · Feb 2007
ReviewClinical management of diabetic foot infection: diagnostics, therapeutics and the future.
Diabetic foot infection accounts for a substantial global burden of morbidity, psychosocial disruption and economic cost. Recommendations for best practice are continuously evolving in parallel with improvements in imaging modalities, development and clinical use of new antimicrobial agents and data surrounding novel adjunctive strategies. We discuss this complex group of infections with a particular emphasis on medical management of osteomyelitis, while also highlighting the importance of a broad multidisciplinary approach to eradicating infection.
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Expert Rev Anti Infect Ther · Feb 2007
ReviewHospital-based strategies to reduce antibiotic resistance: are they valid in the community setting?
Antimicrobial resistance is an increasing problem worldwide in both the hospital and community settings. Various approaches have been proposed and tested mainly in the hospital environment to reduce this problem; however, few of these have been examined from the perspective of applicability to reversing community-based resistance. ⋯ This inexorable increase is occurring in the face of a dearth of new antibiotics for community use and even fewer for treating resistant nosocomial gram-negative species. The possible strategies and consequences are discussed.