Pediatric blood & cancer
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Pediatric blood & cancer · Feb 2004
Comparative StudyMedulloblastoma in childhood: Impact of radiation technique upon the outcome of treatment.
Medulloblastoma is an infratentorial primitive neuroectodermal tumour, diagnosed in paediatric population. The radiotherapy is an essential method of treatment for these tumours. The impact of technical quality of radiation therapy on survival was recently considered. In this study treatment-related variables are analysed with a special focus on radiotherapy technical factors. ⋯ Our results are similar to those published in literature. M0-stage was the most powerful favourable prognostic factor. Male gender and neurological status before radiation treatment were associated with poor survival. Also protracted radiotherapy and quality of radiation technique may have an impact on the outcome.