Emergency medicine Australasia : EMA
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Emerg Med Australas · Apr 2004
Randomized Controlled Trial Clinical TrialCan serum mast cell tryptase help diagnose anaphylaxis?
We aimed to determine the utility of serum mast cell tryptase to diagnose anaphylaxis. ⋯ Clinicians should use caution when using serum tryptase to refute or support a diagnosis of anaphylaxis. Serial tryptase measurement increases sensitivity and specificity. Further studies using serial tryptase determinations in general emergency department practice, perhaps supplemented by histamine determinations, are warranted.