Emergency medicine Australasia : EMA
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Emerg Med Australas · Dec 2013
Randomized Controlled TrialIntravenous 0.9% sodium chloride therapy does not reduce length of stay of alcohol-intoxicated patients in the emergency department: A randomised controlled trial.
I.v. 0.9% sodium chloride (normal saline) is frequently used to treat ED patients with acute alcohol intoxication despite the lack of evidence for its efficacy. ⋯ I.v. normal saline therapy added to observation alone does not decrease ED length of stay compared with observation alone. Intoxication symptom scores and general state of intoxication were similar in both groups. The present study suggests that either approach is reasonable, but observation alone might be preferred as it is less resource intensive.
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Emerg Med Australas · Dec 2013
Randomized Controlled Trial Multicenter StudyRationale and methodology for a multicentre randomised trial of fibrinolysis for pulmonary embolism that includes quality of life outcomes.
Submassive pulmonary embolism (PE) has a low mortality rate but can degrade functional capacity. ⋯ An investigator-initiated, FDA-regulated, multicentre trial of fibrinolysis for submassive PE was conducted, but was limited by screening costs and a low mortality rate. Quality of life measurements might represent a more important patient-centred end-point.
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Emerg Med Australas · Dec 2013
Letter Randomized Controlled TrialAmitriptyline versus tizanidine in the management of tension-type headache in Nepal.