Emergency medicine Australasia : EMA
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Emerg Med Australas · Aug 2020
Randomized Controlled TrialPropofol for migraine in the emergency department: A pilot randomised controlled trial.
To test the administration of intravenous (i.v.) propofol at a procedural sedation dose compared to standard therapy for initial management of migraine in the ED. ⋯ Initial management of migraine with i.v. propofol at procedural sedation doses significantly reduced TTD compared to standard therapy. We did not detect any significant safety concerns although the study was not adequately powered to detect safety of the intervention and requires validation.