The journal of applied laboratory medicine
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Sigma metric calculations provide laboratories an objective means to assess analytical method performance. Methods with higher sigma values are desirable because they are more reliable and may use less frequent quality control in order to maintain optimal performance. Sigma metrics can also serve as a tool when comparing method performance across assay and manufacturer platforms. ⋯ Sigma metrics are comparable for chemistry but not immunoassay platforms. The selection of total allowable error goals led to differences in sigma metrics.