Current Alzheimer research
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The current study evaluated whether the functional connectivity pattern of the thalamo-cortical network in patients with Alzheimer' s disease (AD) and mild cognitive impairment (MCI) would show disease severityrelated alterations. ⋯ Our results revealed disease severity-related alterations of the thalamo-default mode network and thalamocortical connectivity in AD and MCI patients. These results support the hypothesis of network disconnection in AD.