COPD
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Randomized Controlled Trial Comparative Study
Efficacy of tiotropium inhalation powder in african-american patients with chronic obstructive pulmonary disease.
Responsiveness to pharmacologic agents may differ among subpopulations compared with the general population. In patients of African descent, possible differences have been observed for inhaled beta-agonists. However, pharmacologic responsiveness to a long-acting anticholinergic has not been prospectively evaluated. ⋯ Tiotropium significantly improved pulmonary function in African-American COPD patients.
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Randomized Controlled Trial Multicenter Study Comparative Study
Effect of nebulized arformoterol on airway function in COPD: results from two randomized trials.
Arformoterol, a single isomer long-acting beta(2)-agonist, was developed as an inhalation solution for the maintenance treatment of bronchoconstriction in COPD. ⋯ In these trials, COPD subjects administered nebulized arformoterol demonstrated significant and sustained improvement in lung function over 12 weeks.