Taiwanese journal of obstetrics & gynecology
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Taiwan J Obstet Gynecol · Jul 2021
Contingent prenatal screening for frequent aneuploidies with cell-free fetal DNA analysis.
To analyze the results of contingent screening for common aneuploidies at our center from June 2017 to June 2019. ⋯ Our results show that offering cf-DNA testing to women at high risk in traditional tests (including those with risks >1 in 50) significantly reduces false positives and, therefore, the number of invasive tests. Extending the use of cf-DNA testing to intermediate risk categories may be cost effective.