Kathmandu University medical journal (KUMJ)
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Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. ⋯ He had elevated transaminases with detectable muscle weakness. This case highlights the need to consider dermatomyositis with skin lesion and weakness; and the use of aggressive immunosuppressive therapies due to its associated vasculopathies.
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Kathmandu Univ Med J (KUMJ) · Apr 2012
Randomized Controlled TrialPostoperative nausea and vomiting in patients undergoing total abdominal hysterectomy under subarachnoid block: a randomized study of dexamethasone prophylaxis.
Postoperative nausea and vomiting is a common distressing problem in patients undergoing gynaecological surgery under anaesthesia including central neuraxial blockade, which requires frequent medical interventions. ⋯ Use of dexamethasone prior to subarachnoid block in patients undergoing total abdominal hysterectomy significantly reduces the incidence of nausea and vomiting and the requirement of antiemetic in the postoperative period, with better patient satisfaction.
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Kathmandu Univ Med J (KUMJ) · Apr 2012
Perception about the role of anesthesia and anesthesiologist among the paramedical staffs: perspective from a medical college in Nepal.
Anesthesiologists and anesthesia has been considered behind the scene. The image and status of anesthesiologist in the eyes of the medical and lay communities has always been a problem. ⋯ Anesthesiologists have duty to visit patients pre operatively and post operatively. The role inside the theatre and expanding role outside the theatre is poorly known. The awareness about the role of anesthesiologist in operation theatre, in intensive care unit, acute and chronic pain management and emergency care areas should be highlighted to all the staffs.
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Kathmandu Univ Med J (KUMJ) · Oct 2011
Randomized Controlled TrialUse of gabapentin, esmolol or their combination to attenuate haemodynamic response to laryngoscopy and intubation.
Laryngoscopy and intubation increases blood pressure and heart rate. ⋯ Combination of gabapentin and esmolol in this study design is safe and better attenuates both the pressor and tachycardic response to laryngoscopy and intubation, than either agent alone.