Advances in rheumatology (London, England)
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Randomized Controlled Trial Multicenter Study
Multicenter, randomized, double-blind clinical trial to evaluate efficacy and safety of combined glucosamine sulfate and chondroitin sulfate capsules for treating knee osteoarthritis.
To compare the efficacy and safety of a new fixed dose combination of glucosamine sulfate and chondroitin sulfate capsules (GS/CS) versus the fixed dose combination of glucosamine hydrochloride and chondroitin sulfate (Cosamin DS®) in capsules in patients with osteoarthritis (OA) of the knee. ⋯ The new fixed-dose formulation of GS/CS is effective in treating knee OA, presenting a good safety and tolerability profile.