Photomedicine and laser surgery
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Photomed Laser Surg · Jul 2011
Percutaneous diode laser irradiation for lumbar discogenic pain: a clinical study.
The present study evaluated the efficiency of laser irradiation for treating discogenic low back pain. Discogenic low back pain is believed to result from the degeneration and disruption of outer fibers of the intervertebral disc annulus, leading to a cycle of persistent inflammation, damage to the disc matrix, and sensitization of developed annular nociceptors. We selected 11 patients as subjects on the basis of clinical findings and the results of provocative disc blockade. ⋯ Their mean VAS scores at the same post-treatment intervals were 3.09 ± 2.36, 2.4 ± 0.97, 2.7 ± 1.16, 2.1 ± 0.74, 2.1 ± 0.81, and 2.1 ± 0.88, respectively, versus a mean pre-treatment VAS score of 7.64 ± 1.21. The post- versus pre-treatment scores for both the ODI and VAS indicated a statistically significant clinical benefit across the full 24-month follow-up period after laser irradiation. The efficacy of laser irradiation in treating such pain may come from a thermal effect and reductions of intradiscal pressure, of the concentrations of irritant substances, and of the numbers of nociceptors in the affected region.