Scandinavian journal of clinical and laboratory investigation. Supplementum
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Scand J Clin Lab Invest Suppl · Jan 1990
Simultaneous measurements of blood pH, pCO2, pO2 and concentrations of hemoglobin and its derivates--a multicenter study.
During the last few years a need for simultaneous measurements of pH, pCO2, pO2, total hemoglobin concentration, oxygen saturation, carboxyhemoglobin, and methemoglobin has been emphasized. Besides the direct use of such measured quantities a series of algorithms has been developed, especially to describe series of oxygen parameters of the blood. A multicenter study involving 20 hospital centers in Denmark and Sweden was conducted. ⋯ Based on the DPG results, an internal quality procedure has been suggested. Oxygen saturation was calculated based on actual values of pH and pO2 and the standard oxyhemoglobin dissociation curve, and then compared to the measured oxygen saturation. The discrepancy between the calculated and measured values for the different types of blood samples showed that calculation of oxygen saturation should be used with great care for pO2 values below 10 kPa and especially for capillary and umbilical blood samples.