Expert opinion on drug delivery
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Expert Opin Drug Deliv · Jul 2006
ReviewExtended-release opioids for the management of chronic non-malignant pain.
Recent clinical trials have documented the use of extended-release (ER) opioids in the management of chronic non-malignant pain. This manuscript reviews the clinical pharmacology of investigational and current marketed ER opioids. ⋯ Finally, the abuse liability of ER opioids is discussed. Current technologies aimed at defeating the abuse of ER opioids will also be presented.