The journal of sexual medicine
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Case Reports
Central neuropathic pain: an unusual case of painful ejaculation responding to topiramate.
Painful ejaculation (PE) is an uncommon condition and it is usually associated with prostatitis, chronic pelvic pain syndrome, benign prostatic hyperplasia, ejaculatory duct obstruction, radical prostatectomy, and prostate radiation. Topiramate (TPM) is a new antiepileptic drug with recognized efficacy in neuropathic pain. ⋯ TPM may be considered as a valid therapeutic option for the treatment of PE.