The journal of sexual medicine
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Controlled Clinical Trial
Altered sexual and reproductive functions in epileptic men taking carbamazepine.
Epileptic men may experience hormonal changes that may alter semen quality and sexual function. Alterations in male sexual and reproductive parameters may also be due to treatment with antiepileptic drugs to control seizures. ⋯ Epileptic men taking CBZ present with changes in hormonal levels, altered semen quality, ED, and a reduction in coital frequency.
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To provide standard operating procedures for the diagnosis and management of priapism. ⋯ Management of priapism has become increasingly successful as scientific understanding of the pathophysiology and molecular biology of priapism improves. The key to further success in the treatment of priapism is basic research of this uncommon but potentially devastating condition.
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Case Reports
Central neuropathic pain: an unusual case of painful ejaculation responding to topiramate.
Painful ejaculation (PE) is an uncommon condition and it is usually associated with prostatitis, chronic pelvic pain syndrome, benign prostatic hyperplasia, ejaculatory duct obstruction, radical prostatectomy, and prostate radiation. Topiramate (TPM) is a new antiepileptic drug with recognized efficacy in neuropathic pain. ⋯ TPM may be considered as a valid therapeutic option for the treatment of PE.
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Randomized Controlled Trial
Dorsal penile nerve block prior to inflatable penile prosthesis placement: a randomized, placebo-controlled trial.
Dorsal penile nerve block (DPNB) has been previously shown to provide effective analgesia for penile surgeries. To date, few studies have examined the role of DPNB prior to inflatable penile prosthesis (IPP) implantation. ⋯ DPNB is safe and effective for reducing pain in the early postoperative period following penile prosthesis implantation.
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Women with early stage cervical and endometrial cancer may experience complex posttreatment changes to their sexual function, but clinical practice and past research have focused more on the quantity than the perceived quality of sexual life. ⋯ This study found that quality rather than quantity of sexual life is the best predictor of overall sexual function among women treated for early stage cervical and endometrial cancer, indicating the importance of including quality indices in posttreatment sexual assessment in clinical practice and research studies.