Pharmacogenetics and genomics
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Pharmacogenet. Genomics · Feb 2010
Development of a Pharmacogenetic Predictive Test in asthma: proof of concept.
To assess the feasibility of developing a Combined Clinical and Pharmacogenetic Predictive Test, comprised of multiple single nucleotide polymorphisms (SNPs) that is associated with poor bronchodilator response (BDR). ⋯ Our finding that genetic polymorphisms with a clinical trait are associated with BDR suggests that there is promise in using multiple genetic polymorphisms simultaneously to predict which asthmatics are likely to respond poorly to bronchodilators.