Pharmacogenetics and genomics
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Pharmacogenet. Genomics · May 2013
Expression of mRNA transcripts encoding membrane transporters detected with whole transcriptome sequencing of human brain and liver.
Membrane transporters control the influx and efflux of endogenous and xenobiotic substrates, including nutrients and drugs, across cellular membranes. ⋯ The results obtained with RNAseq provide detailed information on transporter mRNA expression at the molecular level, affording new avenues for the study of membrane transport, with relevance to drug efficacy and toxicity.