Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
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Association of obstructive sleep apnea severity with the composition of the upper airway microbiome.
Although the airway mucosal system plays a pivotal role in the pathogenesis of obstructive sleep apnea (OSA), the underlying disease mechanism remains unclear. The microbiome greatly impacts human health and disease, particularly in the mucosa, where it can have direct interactions. In this study, we aimed to analyze the microbiome composition in the upper airway mucosa of individuals with and without OSA to identify potential disease severity-related microbial signatures. ⋯ The upper airway microbiome of older patients with mild-moderate OSA exhibited minor differences in composition compared with that of individuals without OSA, possibly owing to environmental changes in the upper airway mucosa resulting from recurrent airway obstruction and intermittent hypoxia in patients with OSA.
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To investigate gender distribution of US sleep professionals who received major recognition awards over a 40-year period from the 2 national sleep societies: the American Academy of Sleep Medicine and the Sleep Research Society. ⋯ Naime S, Karroum EG. Women are underrepresented in major US sleep societies recognition awards. J Clin Sleep Med. 2021;17(8):1665-1673.