Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease
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Observational Study
Skin microvascular function in patients with type 1 diabetes: An observational study from the onset of diabetes.
The development of disturbances in skin microcirculation in type 1 diabetes is not well characterised. We assessed skin microcirculation longitudinally from the onset of diabetes up to 29 years of duration to investigate when such disturbances start. ⋯ Functional disturbances in total skin microcirculation were observed after seven years in patients with type 1 diabetes and preceded diabetic complications such as retinopathy.