Journal of Zhejiang University. Science. B
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J Zhejiang Univ Sci B · Dec 2005
Controlled Clinical TrialStudy on EEG power and coherence in patients with mild cognitive impairment during working memory task.
To investigate the features of electroencephalography (EEG) power and coherence at rest and during a working memory task of patients with mild cognitive impairment (MCI). Thirty-five patients (17 males, 18 females; 52-71 years old) and 34 sex- and age-matched controls (17 males, 17 females; 51-63 years old) were recruited in the present study. Mini-Mental State Examination (MMSE) of 35 patients with MCI and 34 normal controls revealed that the scores of MCI patients did not differ significantly from those of normal controls (P>0.05). ⋯ These findings comprise evidence that MCI patients have higher EEG power at rest, and higher EEG power and coherence during working conditions. It suggests that MCI may be associated with compensatory processes at rest and during working memory tasks. Moreover, failure of normal cortical connections may be exist in MCI patients.
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J Zhejiang Univ Sci B · Dec 2005
Randomized Controlled TrialComparison of low-molecular-weight-heparin and unfractionated heparin for acute PTE.
Acute pulmonary thromboembolism (PTE) is a serious high mortality pulmonary vascular disease whose effective treatment decreases morbidity and mortality. To determine if low-molecular-weight-heparin (LMWH) is clinically as efficient and safe as unfractionated heparin (UH) in patients with diagnosis of acute non-massive PTE, our study compares the efficacy, adverse effects and costs of LMWH and UH. ⋯ LMWH and UH are equally effective for treatment of non-massive acute PTE, but LMWH may have a lower prevalence of complications and is less expensive.