Journal of biomechanics
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Journal of biomechanics · Dec 2020
Spring-loaded inverted pendulum modeling improves neural network estimation of ground reaction forces.
Inertial-measurement-unit (IMU)-based wearable gait-monitoring systems provide kinematic information but kinetic information, such as ground reaction force (GRF) are often needed to assess gait symmetry and joint loading. Recent studies have reported methods for predicting GRFs from IMU measurement data by using artificial neural networks (ANNs). To obtain reliable predictions, the ANN requires a large number of measurement inputs at the cost of wearable convenience. ⋯ Leave-one-subject-out cross-validation was performed with normalized root mean square error and r as quantitative measures of prediction performance. The vertical and anteroposterior (AP) GRFs obtained using both methods agreed well with the experimental data, but Method 2 yielded improved predictions of AP GRF compared to Method 1 (p = 0.005). These results imply that knowledge of the dynamic characteristics of walking, combined with a neural network, could enhance the efficiency and accuracy of GRF prediction and help resolve the tradeoff between information richness and wearable convenience of wearable technologies.
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Journal of biomechanics · Nov 2020
Between-session reliability of subject-specific musculoskeletal models of the spine derived from optoelectronic motion capture data.
This study evaluated the between-session reliability of creating subject-specific musculoskeletal models with optoelectronic motion capture data, and using them to estimate spine loading. Nineteen healthy participants aged 24-74 years underwent the same set of measurements on two separate occasions. Retroreflective markers were placed on anatomical regions, including C7, T1, T4, T5, T8, T9, T12 and L1 spinous processes, pelvis, upper and lower limbs, and head. ⋯ Spine curvature measures showed excellent reliability (ICC = 0.79-0.91) and body scaling segments showed fair to excellent reliability (ICC = 0.46-0.95). We found that musculoskeletal models showed mostly excellent between-session reliability to estimate spine loading, with 91% of ICC values > 0.75 for all activities. This information is a necessary precursor for using motion capture data to estimate spine loading from subject-specific musculoskeletal models, and suggests that marker data will deliver reproducible subject-specific models and estimates of spine loading.
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Journal of biomechanics · Nov 2020
A comparison of balance-correcting responses induced with platform-translation and shoulder-pull perturbation methods.
The understanding of reactive balance control mechanisms in humans emanates from studies utilizing a variety of perturbation methods, instructions, and sensory conditions. The use of different perturbation methods may produce method-specific balance-correcting responses. This study evaluated balance-correcting responses induced with platform-translation and shoulder-pull methods with equilibrated perturbation intensities, and whether the absence of vision affects balance-correcting responses differently between perturbation methods. ⋯ During platform-translation trials participants demonstrated smaller MOS which placed them in a less favorable circumstance for balance recovery. Platform-translation appears to be more challenging than shoulder-pull perturbation in terms of balance recovery. This study underscores that caution is required when interpreting results of studies utilizing different perturbation paradigms.
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Journal of biomechanics · May 2020
Effects of nucleus pulposus location on spinal loads and joint centers of rotation and reaction during forward flexion: A combined finite element and Musculoskeletal study.
The mechanical environment of the intervertebral disc and spinal loads are intimately associated with low back pain (LBP) caused by mechanical load. The cause and effect relationship between postures and pain has been therapeutically investigated and widely used to guide patient care. Shift of the nucleus pulposus (NP) inside the intervertebral disc when the spine changes posture in the sagittal plane, known also as NP migration, has been observed and quantified in in-vivo studies. ⋯ The results showed that intradiscal pressure (IDP) and compressive force are sensitive to the nucleus location while the effects on the center of rotation (CoR), center of reaction (CTR) and moment rotation curves were negligible. Also, our findings revealed that FE models should consider the effects of NP location during bending to predict more realistic results as the nucleus displacement caused by disc bulge predicted by these models is much smaller than the real shift observed in in-vivo. In addition, this study confirmed that position of the rigid joint in MSK models that fix this latter to the CoR, must be modelled carefully for more accurate muscle forces and spinal loads prediction.
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Journal of biomechanics · May 2020
Finite element analysis of MitraClip procedure on a patient-specific model with functional mitral regurgitation.
Mitral valve (MV) repair with the MitraClip device has been shown to reduce mitral regurgitation severity and improve clinical outcomes in symptomatic patients at high surgical risk. MitraClip was recently approved in the US for the treatment of functional mitral regurgitation (FMR), which significantly expands the number of patients that can be treated with this device. This study aims to quantify the morphologic changes and evaluate the biomechanical interaction between the MitraClip device and the mitral apparatus of a real patient case with FMR using computational modeling. ⋯ Anterior and posterior leaflet peak stresses increased by up to 64% and 62% after clip placement, respectively, and were located at the region of clip grasp. Similarly, anterior and posterior leaflet peak strains increased by up to 20% and 10%, respectively. FE modeling, as used here, can be a powerful tool to examine the complex MitraClip-host biomechanical interaction.