Medicinal chemistry
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Medicinal chemistry · Jan 2017
ReviewApplication of Machine Learning Approaches for Protein-protein Interactions Prediction.
Proteomics endeavors to study the structures, functions and interactions of proteins. Information of the protein-protein interactions (PPIs) helps to improve our knowledge of the functions and the 3D structures of proteins. Thus determining the PPIs is essential for the study of the proteomics. ⋯ This review presents the application of machine learning approaches in predicting PPI. Many examples of success in identification and prediction in the area of PPI prediction have been discussed, and the PPIs research is still in progress.